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Twelve metabolites of the artificial cannabinoid, EAM-2201, have been tentatively recognized in human hepatocytes in vitro, As well as in human liver and urine specimens in vivo for The 1st time. There was a distinct distinction in metabolism profile in between the in vitro As well as in vivo benefits.
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Then, the inhibitor focus that supports 50 % the maximal price of inhibition (Ki) and maximal charge of enzyme inhibition (kinact) values have been calculated working with the subsequent equation with Enzyme Kinetics program:
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